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KMID : 0948320050050010094
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Konyang Medical Journal
2005 Volume.5 No. 1 p.94 ~ p.98
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The Clinical Significance of Ocular Dimensions in Patients with Open Angle Glaucoma and Ocular Hypertension
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Hahm I-Rum
Sohn Yong-Ho
Kim Hwang-Ki
Chung Yun-Suk
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Abstract
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Purpose: To determine characteristics of ocular dimensions in glaucoma and ocular hypertension and possible correlations between age, tonometry and ocular dimensions.
Methods: Randomly chosen 101 eyes of 101 patients who have not taken any intraocular pressure (IOP)-lowering medications were studied. 21 eyes were diagnosed as primary open angle glaucoma (POAG), 13 eyes as ocular hypertension, 48 eyes as normal tension glaucoma, and 19 eyes were diagnosed as normal. Tonometry, central corneal thickness (CCT), anterior chamber depth, lens thickness, and axial length were measured.
Results: CCT was thinnest in eyes with normal tension glaucoma (534±5 μm), thickest in eyes with ocular hypertension (586±14 μm), and intermediate in eyes with POAG and healthy eyes (539±6 μm and 548±6 μm, respectively). These differences were statistically significant (P=0.0007). Goldmann applanation tonometry and CCT were weakly correlated (r=0.16, P=0.255). Lens thickness was strongly correlated with age (r=0.68, P<0.0001). Anterior chamber depth was negatively correlated with lens thickness and age (r=-0.35, P=0.014 and r=-0.55 P<0.0001). Axial length was correlated with anterior chamber depth and age (r=0.72 P<0.0001 and r=-0.44 P=0.001).
Conclusions: The influence of central corneal thickness on the accuracy of IOP measurement with Goldmann pplanation tonometry appears to be small and not clinically relevant. When corneal thickness is deviated from normal, it would be desirable to take this into account in diagnosis and management of glaucoma.
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KEYWORD
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Central comeal thickness, Ocular dimension, Tonometry
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